![\"\"](\"https:\/\/redenoticiaz.com.br\/litoralsp\/wp-content\/uploads\/sites\/3\/2021\/03\/doria-butanvac-1024x683.jpg\")
<\/a><\/p>\nA iniciativa do novo imunizante faz parte de um cons\u00f3rcio internacional do qual o Instituto Butantan \u00e9 o principal produtor, respons\u00e1vel por 85% da capacidade total, e tem o compromisso de fornecer essa vacina ao Brasil e aos pa\u00edses de baixa e m\u00e9dia renda. A produ\u00e7\u00e3o-piloto do composto j\u00e1 foi finalizada para aplica\u00e7\u00e3o em volunt\u00e1rios humanos durante os testes.<\/p>\n
Tecnologia ButanVac<\/h4>\n
Para a produ\u00e7\u00e3o da ButanVac o instituto dever\u00e1 usar tecnologia j\u00e1 dispon\u00edvel em sua f\u00e1brica de vacinas contra a gripe, a partir do cultivo de cepas em ovos de galinha, que gera doses de vacinas inativadas, feitas com fragmentos de v\u00edrus mortos.<\/p>\n
Segundo Ricardo Palacios, diretor m\u00e9dico de pesquisa cl\u00ednica do Instituto Butantan, a nova vacina brasileira ter\u00e1 perfil alto de seguran\u00e7a. \u201cN\u00f3s sabemos produzir a ButanVac, temos tecnologia para isso, e sabemos tamb\u00e9m que vacinas inativadas s\u00e3o eficazes contra a COVID-19. Poder entregar mais vacinas \u00e9 o que precisamos em um momento t\u00e3o cr\u00edtico\u201d, explica.<\/p>\n
Diretor-presidente do Butantan, Dimas Covas afirma que a tecnologia utilizada na ButanVac \u00e9 uma forma de aproveitar o conhecimento adquirido no desenvolvimento da CoronaVac, vacina desenvolvida em parceria com a biofarmac\u00eautica Sinovac, j\u00e1 dispon\u00edvel para a popula\u00e7\u00e3o brasileira.<\/p>\n
\u201cEntendemos a necessidade de ampliar a capacidade de produ\u00e7\u00e3o de vacinas contra o coronav\u00edrus e da urg\u00eancia do Brasil e de outros pa\u00edses em desenvolvimento de receberem o produto de uma institui\u00e7\u00e3o com a credibilidade do Butantan. Em raz\u00e3o do panorama global, abrimos o leque de op\u00e7\u00f5es para oferecer aos governos mais uma forma de contribuir no controle da pandemia no pa\u00eds e no mundo\u201d, afirma. Segundo ele, a parceria com a a Sinovac ser\u00e1 mantida, e n\u00e3o haver\u00e1 nenhuma altera\u00e7\u00e3o no cronograma dos insumos vindos da China.<\/p>\n
ButanVac ainda este ano<\/h4>\n
O diretor-presidente do Butantan tamb\u00e9m afirmou que ser\u00e1 poss\u00edvel entregar a vacina brasileira ainda neste ano. \u201cAp\u00f3s o final da produ\u00e7\u00e3o da vacina contra Influenza, em maio, poderemos iniciar imediatamente a produ\u00e7\u00e3o da Butanvac. Atualmente, nossa f\u00e1brica envasa a Influenza e a CoronaVac. Estamos em pleno vapor\u201d, afirma Dimas Covas.<\/p>\n
A tecnologia da ButanVac utiliza um vetor viral que cont\u00e9m a prote\u00edna Spike do coronav\u00edrus de forma \u00edntegra. O v\u00edrus utilizado como vetor nesta vacina \u00e9 o da Doen\u00e7a de Newcastle, uma infec\u00e7\u00e3o que afeta aves. Por esta raz\u00e3o, o v\u00edrus se desenvolve bem em ovos embrionados, permitindo efici\u00eancia produtiva num processo similar ao utilizado na vacina de influenza. O v\u00edrus da doen\u00e7a de Newcastle n\u00e3o causa sintomas em seres humanos, constituindo-se como alternativa muito segura na produ\u00e7\u00e3o. O v\u00edrus \u00e9 inativado para a formula\u00e7\u00e3o da vacina, facilitando sua estabilidade e deixando o imunizante ainda mais seguro.<\/p>\n
A pesquisa cl\u00ednica em humanos do novo imunizante ser\u00e1 realizada em conformidade com altos padr\u00f5es internacionais \u00e9ticos e de qualidade. Os resultados v\u00e3o determinar se a vacina \u00e9 segura e tem resposta imune capaz de prevenir a COVID-19.<\/p>\n","protected":false},"excerpt":{"rendered":"
O Instituto Butantan, iniciou o desenvolvimento e a produ\u00e7\u00e3o-piloto da primeira vacina brasileira, ButanVac, contra o novo coronav\u00edrus. A expectativa \u00e9 que os ensaios cl\u00ednicos de fases 1 e 2 em humanos com o novo imunizante comecem j\u00e1 em abril, ap\u00f3s autoriza\u00e7\u00e3o da Anvisa (Ag\u00eancia Nacional de Vigil\u00e2ncia Sanit\u00e1ria). \u201cEste \u00e9 um an\u00fancio hist\u00f3rico para …<\/p>\n","protected":false},"author":5,"featured_media":6227,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[23],"tags":[16694,16693,16691,16692],"class_list":["post-6225","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saude","tag-butantan-desenvolve-primeira-vacina-brasileira","tag-butantan-vacina-brasileira","tag-butanvac","tag-primeira-vacina-brasileira"],"yoast_head":"\n
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